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A protein kinase is a type of kinase enzyme that phosphorylates other molecules by chemically attaching phosphate groups to them. By altering the activity of an enzyme, a protein’s position within the cell, or its connection with other proteins, phosphorylation typically causes a functional change in the target protein (substrate). About 518 protein kinase genes, or 2% of all human genes, are found in the human genome. The activity of kinases is known to modify up to 30% of all human proteins[citation needed], and they are known to control the majority of cellular pathways, particularly those involved in signal transduction. The pseudokinase subfamily of protein kinases, which have peculiar characteristics such aberrant nucleotide binding and weak, are also found in bacteria and plants.


For more: human phospho kinase antibody array

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