FXR1 activates sperm cell translation and promotes sperm formation through phase separation

In mammals, spermatogenesis (the differentiation of male germ cells after meiosis) is a highly coordinated developmental process controlled by a set of genes collectively known as spermatogenesis genes.   Given that nuclear condensation during spermatogenesis gradually stops transcription, spermatogenic genes are transcribed early during the early stages of male reproductive development and stored as translationally […]